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"Is
there any point to
which you would wish
to draw my attention?"
"To the curious incident of
the dog in the night time."
"The dog did nothing
in the night time."
"That was the curious
incident," remarked
Sherlock Holmes.
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By Fintan Dunne, 30 Dec '02
Editor www.SickofDoctors.com
Those of you in the US can tuck into the bacon
and eggs with gay abandon. Latest analysis shows that heart disease
has but tenuous links to diet and has trends that give lie to
the cholesterol theory. Much of what we have been taught now looks
dubious.

James Le Fanu, a London-based general practitioner, writing recently
in the British Medical Journal, asserts that the WHO-Monica study
of trends in heart disease in 27 countries, shows coronary mortality
in middle-aged US males peaked in the mid-1960's and has since
declined back to pre-1940's levels.
Dr. Le Fanu did not get his data directly from the WHO report.
The voluminous tome had many tables showing such as: "the
average annual percentage change in coronary events over the last
five years." But it was far too coy to provide the historical
data in the stark terms of Dr. Le Fanu's representation.
His laborious analysis of the source data shows the abrupt reversal
of the rising trend in the mid-1960's. That's a little sudden
to have resulted from mass changes in diet, he maintains.
So order that egg sunny side up.
THE SOUND OF NO DOG BARKING
There
is good reason for the coyness of the heart disease pundits. To
explain, Dr. Le Fanu adopts the persona of Sherlock Holmes in
the Conan Doyle classic, "Silver Blaze."
In the novel, while investigating an apparent murder during the
overnight stealing of a racehorse, Holmes was intrigued by what
did not happen. The stable dog never barked. It must have known
the perpetrator, Holmes concluded.
The heart disease establishment is similarly mute.
In Canada and Australia rates followed exactly the same pattern
as the US. In Western Europe a similar trend appeared, albeit
with a ten year lag --peaking in the 1970's. Dr. Le Fanu doesn't
accept that a few hundred million people in the US, Australia
and Canada simultaneously and collectively decided to suddenly
improve their diets. Or that Western Europeans followed suit en
masse ten years later.
Is all this news to you? Didn't you hear the dog bark?
A CASE OF CURIOUS ANOMALIES
The heart disease establishment dog didn't bark because it recognizes
the perpetrator. The words "cozy cartel" come to mind.
Were that dog to bark the truth, we might only awaken and realize
we have been robbed.
The data do not fit. For US coronary mortality to have fallen
in the 1960's any diet-dependent changes would have had to take
place around 1950. America in the 1950's was in love with all
the wrong kinds of food. Yet by 1965 coronary mortality was falling.
And it has continued to decline even as Americans have grown more
obese.
Call Holmes. Something is wrong with this picture.
The outlook for big breakfasts is less sunny in Eastern Europe.
Their rates of mortality are only now climbing to the rates the
US experienced in the 1940's. The trite assumption might be that
they are only recently discovering the downside of a 'Big Mac'
lifestyle. But if we accept that diet is too facile an explanation,
what is the alternative?
Coming up with a consistent answer is going to be difficult, as
the data can readily mislead, according to Dr. Le Fanu. Cross
cultural comparisons can readily differ from comparisons within
cultures.
FAR FROM ALIMENTARY, DEAR WATSON
For
example, viewed worldwide, the more dairy product in diet, the
more heart disease. But among Western Europeans, the Finnish heart
disease rate is four times the rate in Switzerland even though
dairy consumption is equivalent.
It would be convenient if we could attribute that anomaly to genetic
differences between Finns and Swiss. But, studies of migrants
to the US have shown that genes offer no overriding protection.
Swedish immigrants, whose native diet has a similar fat content
to the US, soon double their heart disease rates to match that
in their adopted environment.
Flailing around for coherence as our certainties dissolve, perhaps
it is time to jettison all our ill-founded assumptions and go
back to the drawing board on heart disease risks.
From an epidemiological viewpoint, Dr. Le Fanu specualtes that
the fall and rise of heart disease looks more like a biological
phenomenon, like an infectious outbreak, than a lifestyle issue.
Perhaps,
but a host of other possibilities beckon. In any event, this is
far from being a simple case of cholesterol. Diet is a dud.
All of which is still news to the many who live by the Gospel
of the Food Pyramid. The dietary moralists are not about to remove
the smokescreen around the data and expose their big fat lie.
Not alone will that dog not bark. That dog won't even hunt.
BMJ Article by Dr. Le Fanu
http://bmj.com/cgi/content/full/325/7378/1490
SickofDoctors.com
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